Cannabis has varied effects from person to person ranging from red eyes and dry mouth to dizziness and paranoia. This is a well-established fact within the cannabis community. However, recent studies show that in some people, the use of cannabinoids can affect their body temperature. How Marijuana Make You Feel Cold The studies show that marijuana can affect your body’s thermoregulation functions. Or put simply, the ability of the body to regulate its internal temperature. Effectively, this means that the compounds found in cannabis have the ability to make you feel either hot or cold. Of the two, the most common effect of consuming cannabis would be a drop in body temperature. Common names for this is “weed chills,” but the more accurate term is THC- induced hypothermia. This drop in temperature is hat may cause shaking after smoking weed, but don’t be alarmed, in this case, hypothermia does not refer to the life-threatening medical emergency; instead, it is just the slight drop in internal body temperature; just enough to cause shivering. On the other hand of the spectrum, marijuana use can also cause an increase in body temperature. This is as a result of CBD; another compound found in cannabis. This increase in body temperature is what is referred to as cannabinoid-induced hyperthermia. It should be noted that these effects are dependent on the dose of either THC or CBD you consume. The higher the dose of THC then the more likely you will experience THC induced hypothermia. Alternately, microdoses of marijuana are likely to cause an increase in temperature leading to CBD induced hyperthermia. Cannabis and TRP ChannelsTRP channels refer to transient receptor potential (TRP) channels. These are essentially pathways within the human body that transport specific molecules. It is these pathways that enable you to feel temperature and pain and also sensory perceptions like the taste, and also chemoreception, mechanoreception, and photoreception. There exists a wide range of transient receptor potential channels in the human body, but research has shown that those that are most affected with cannabis are: TRPV1 whose activation induces hypothermia, and TRPV8 which induces hyperthermia, according to a 2011 study. Although research has shown that the TRP channels are at play in the temperature fluctuations due to cannabis, additional research is necessary because there are findings that suggest that marijuana may affect the body in some more complicated way. The research has shown that cannabinoid receptors have a significant influence over temperature regulation. These receptors make up part of an extensive endocannabinoid system (ECS). Although much of the research about the effects of cannabis on body temperature is conducted on rodents, it is possible to deduce the impact it has on humans based on the results. The TRPA-1 Receptor and Weight Loss TRPA-1 is involved in a wide range of processes in the ECS and the human body including; nociception, thermosensation and quite recently discovered energy homeostasis.
Energy homeostasis is the function in the body that is responsible for maintaining healthy body weight through the control of food intake and also in regulating energy expenditure in the body. Evidence shows that TRPV-1 may be dysregulated in obesity, contributing to the development of the disease. TRP channels also appear to influence pancreatic insulin secretion. Dietary supplementation with TRPV-1 agonists such as capsaicin and THC has shown some conflicting results, with some studies showing a reduction in food intake and an increase in energy expenditure while others show the opposite. Considering this involvement in the regulation of energy and glucose homeostasis and the dysregulation in obesity, TRPV-1 may then be a target for weight loss therapy and diabetes. TRPV-1 also interacts with the endocannabinoid system such that; endocannabinoids such as AEA are endogenous ligands for TRPV-1. Agonists of TRPV-1 have shown an anti-obesity effect in rodents and reduced eating in humans. It is also evident that endocannabinoid receptor CB1 can enhance or inhibit TRP channel activity depending on whether or not it activates or deactivates the specific pathways for the functions, furthermore, this interaction appears to be dependent on the dose of the agonist consumed. The bottom line is the body temperature changes induced by marijuana consumption such as the weed chills or twitching while high are usually mild and will dissipate quickly. It is also essential to keep in mind the amount of cannabis you consume directly affects the resulting body temperature changes. With this in mind, it is, therefore, possible for you to determine or anticipate the kind of effect that will ensue after the consumption of marijuana. An increase in THC rich cannabis will result in a decrease in body temperature, perhaps just what you are looking for on a hot summer day.
24 Comments
3/5/2020 11:49:59 am
I always grow my own at home using the best 5x5 grow tents.
Reply
Robert Coates
5/5/2020 03:11:35 pm
I think you have it backwards. When temp goes up, you feel chilly and may get the shakes. If it goes down, you should feel too warm.
Reply
Genius
11/7/2021 06:14:06 am
I honestly think this article is full of bullshit
Reply
Mik
11/19/2021 02:30:04 pm
You’re mistaking changes in body temp with having a fever. Fevers make you cold because your brain has raised its temperature threshold to fight an infection. Otherwise, rising body temp is going to make you feel hot. That’s how hot flashes work.
Reply
CAMERON
4/23/2022 11:18:13 am
YEA IT MAKE YOU HOT
Reply
I suffer from some really severe hot flashes on top of being hot most of the time naturally. When I’m high I feel very cold and I love it. Has there been any peer viewed empirical research studies that hypothesize on how marijuana affects menopausal women; and possibly info on drugs derived from marijuana to control body temperature synthetically or naturally? CBD?
Reply
8/1/2022 03:13:31 am
Really informative article, I had the opportunity to learn a lot, thank you. https://takipcisatinalz.com/takipci-2/
Reply
8/2/2022 06:03:53 am
Really informative article, I had the opportunity to learn a lot, thank you. https://takipcialdim.com/ucuz-takipci-satin-al/
Reply
8/3/2022 12:28:35 am
Really informative article, I had the opportunity to learn a lot, thank you. https://www.takipcikenti.com/instagram/turk-takipci/
Reply
9/9/2022 06:44:02 pm
https://taraftarium24izle.net/category/futbol/
Reply
9/24/2022 07:13:40 am
sikayetgir.com En trend şikayetvar yorumlarını sizin için yayınlıyor.
Reply
10/1/2022 03:23:15 pm
https://devletbasvurusu.com/ibb-promosyonlari-27-bin-tl-olarak-aciklandi/
Reply
12/20/2022 05:48:25 pm
İnstagram takipçi satın almak istiyorsan tıkla.
Reply
1/7/2023 10:26:39 pm
100 tl deneme bonusu veren siteleri öğrenmek istiyorsan tıkla.
Reply
6/7/2023 02:46:46 am
For true fans of this thread I will address is a free online!
Reply
6/29/2023 07:06:56 pm
En iyi aksaray ilan sitesi burada. https://aksaray.escorthun.com/
Reply
Leave a Reply. |
AuthorCannabis enthusiasts who believe that each one of us has the right to know the truth about this fabulous, natural alternative. |